Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects. Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.
Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.
Frequency and voltage both affect phenytoin binding.
There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.
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The answer is D, serving as a primary source of energy for the body.
Answer:
Metaphase
Explanation:
The M phase of the cell cycle is the phase during which the nuclear content and cellular content is distributed. The distribution of the nuclear content takes place in four phases: prophase, metaphase, anaphase and telophase.
The homologous chromosomes are aligned at the equatorial plate during the metaphase after which the chromosomes separate. The phase during which the separation of the chromosomes takes place is known as anaphase so the phase before the anaphase is the phase during which the chromatids are not separated that is the metaphase.
Thus, metaphase is the correct answer.
Answer:
the male reproductive cell is called a(n) sperm
the female reproductive cell is called a(n) egg
when the male and female cells join during fertilization, a(n) embryo forms
Explanation
During a males life, the sperm forms. During a females life, the egg forms. When a man and a woman fall in love, the reproduce, causing the sperm and egg join to form a embryo
