Answer:
The Various Kinases that is activated after the breaks in DNA is after the activation of ATM serine threonine kinase which helps in phosphorylation of other DNA replication check proteins, p53 protein (tumor suppressor protein) etc.
Explanation:
ATM activated by MRN complex at the site of DNA double stranded breaks by phosphorylation. MRN complex activity on ATM induces a conformational change in ATM kinase. So it can bind to its various substrate molecules that helps in DNA replication cycle arrest.
ATM phosphorylates CHK2 protein a product of CHEK2 gene, also known as effector kinases that phosphorylates and helps in deactivation of cyclin dependent kinases (CDKs) that helps in the prevention of progression of mitotic phase.
ATM also phosphorylates the inhibitors of p53 proteins which leads to the overexpression of p21, an inhibitor of (CDKs).
Answer:
A protein-coding gene has an open reading frame (ORF) that make easier its identification
Explanation:
During translation, the messenger RNA (mRNA) is read by the ribosomes as triplets of nucleotides called codons in the open reading frame (ORF). An ORF can be defined as a gene fragment composed of codons which are translated into amino acids in a polypeptide chain. According to the genetic code, the information encoded by these codons will specify the sequence of amino acids in the protein, as well as the start codon and stop codons of the protein-coding genes. A start codon (AUG) is a site at which translation into protein begins, while stop codons (UAA, UAG, and UGA) mark the site at which translation ends. Moreover, non-coding RNAs (ncRNAs) don't have ORFs because they do not encode for proteins, and therefore their identification is more difficult.
Answer:
The phosphates provide energy for the bond between each nucleotide.
Explanation:
When each nucleotide is being bound, the two extra phosphates provide the energy needed for it to form the bind between each nucleotide that's being added to the RNA. Without this energy, the RNA wouldn't be able to form due to the lack of enough energy.
nucleic acids. certain proteins. cell membranes. certain carbohydrates.
Q. What connects the throat and the trachea contains the vocal cords allows you to speak and make sounds structure?
A. The larynx