<h2>Glucose production by liver</h2>
Explanation:
- Most of this secretory organ comprises of acinar or exocrine cells that discharge the pancreatic juice containing stomach related compounds, for example, amylase, pancreatic lipase, and trypsinogen, into the pipes, that is, the fundamental pancreatic and the extrapancreatic channel
- The endocrine cells are bunched together, along these lines shaping the supposed islets of Langerhans, which are little, island-like structures inside the exocrine pancreatic tissue that represents just 1–2% of the whole organ
- drop in glucose triggers the arrival of glucagon by the pancreas. in the liver, glucagon enacts glycogen phosphorylase by animating its cAMP-subordinate phosphorylation and invigorates gluconeogenesis by bringing down [fructose 2,6 bisphosphate] consequently animating FB Pase-1
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Answer:
C. The chance of survival decreases when there is intraspecific competition for resources among surviving yearlings
Explanation:
The survival rate of the offspring of the fish species will decrease as a result of the huge number of eggs produced giving rise to overpopulation. Pressure will be on the limited available resources. As a result of this, Intraspecific competition would occur as members of the same fish species would compete for the limited resources.
Interference and exploitation competition are two types of Intraspecific competition that can reduce the population size of the fish species.
For Interference competition, the dominant and stronger members would secure adequate supply of the limited resources to detriment of the weaker and less dominant ones. This leads to the death of those members that are weak to compete successfully, thereby leading to a reduction in population size.
In exploitation competition, it involves all individual members of the fish species sharing the limited resources equally, while none of them gets an adequate amount. With time, a great size of the population decrease would be noticed when compared to that of Interference competition.
Decomposer. Hope it helps!
