They are different in structure as one serves in an open system (lymphatic system) while the other serves is closed system (circulatory system).
Hope this helps!
*This question is common, so this answer I use a lot. I copied my own work.*
The correct answer is that bones do not have a role in glycogen production. Glycogen is only produced by two organs of the body; the muscles and the liver. Bones and bone structures function to support movement by serving as insertions for the muscles. The tissue inside the bone is called the bone marrow; which is divided into red marrow (functions for blood cell formation) and yellow marrow (functions to store fat).
Which signal are you talking about?
Malfunction might lead to organ diseases, and might alter the body metabolism.