Answer:
1. In whom did non-disjunction occur?
Non-disjunction occur in the Woman;
2. In meiosis I or meiosis II?
there is not enough information to tell if the nondisjunction happened in meiosis I or II.
Explanation:
Both Turner syndrome and hemophilia, a blood-clotting disorder, are X-linked
Turner syndrome is due to a chromosomal abnormality in which all or part of one of the X chromosomes is missing or altered. While most people have 46 chromosomes, people with TS usually have 45. The chromosomal abnormality may be present in just some cells in which case it is known as TS with mosaicism. In these cases, the symptoms are usually fewer and possibly none occur at all.
Hemophilia A is an X-linked, recessive disorder caused by deficiency of functional plasma clotting factor VIII (FVIII), which may be inherited or arise from spontaneous mutation.
Hence, the disjunction occur in the woman.
A disease that is acquired during development of the infant in the uterus and exists at or dating from birth is called congenital disease.
“When you last renewed your driver's license, you may have checked the box to become an organ donor. Or you may have skipped it. And you may have chosen either option without thinking about it too much, or without truly understanding the decision you were making.
Choosing whether to be an organ donor is certainly a personal decision, but it really is a heroic one - and one that you, as an individual, can make on your own.
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One organ and tissue donor can save and enhance the lives of up to 50 people. An organ donor can give a second chance at life to up to eight people. Through tissue donation, a donor can enhance the lives of countless others through bone donations to repair fractures and prevent amputations, skin donations to heal burn patients and heart valve donations to repair life-threatening defects. Donors can also donate their corneas, which can give the gift of sight to recipients.
Last year, more than 30,000 organ transplants were performed in the United States.
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According to the Gift of Life Donor Program, over 8,400 Pennsylvanians are waiting for a life-saving organ transplant. Residents who have a driver's license or state identification card can go online and add the donor designation to their record. You can also register online at www.donors1.org.
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Relative risk [RR] = [no of diseased patient in group 1/total no of people in the group 1] divided by [no of diseased patient in group 2/total no of people in group 2]
RR =[ 5/2000] divided by [5/1000] = 0,0025/0.005 = 0.5
Therefore the relative risk of the sample is 0.5.
