Answer: Aristotle's and Linnaeus's classification systems both divided all life into two groups: plant and animal.
Answer:
Ribosomes
Explanation:
hope that helps and sorry if it's wrong
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Answer:
Due evolution, discoveries and having both characteristics.
Explanation:
The Kingdom of Life change due to evolution in the body of organisms, discoveries of new organisms that are different from plants and animals. There are some organisms that have both plant and animal characteristics so it can't be placed in plant or animal kingdom so that's why the kingdom of life changes from two kingdom system to 5 kingdom system.
As solar energy interacts with carbon dioxide, water vapor, and several other gases in the troposphere, it warms the troposphere process known as the Green house effect.
- Troposphere is the lower most part of the earth's atmosphere comprises of Nitrogen, Oxygen, Argon, Carbon dioxide and Water vapour.
- Carbondioxide, water vapour and other gases like methane are concentrated highly in the Trophosphere due to some human activities (Industrial revolution).
- Such excess Green house gases forms a shield layer which retains the heat by trapping the long wave radiation of solar energy in troposphere. As a result, global warming and abnormal weather conditions occurs in the planet.
Learn more about the Green house effect on brainly.com/question/21469833.
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