A phagocytic cell has a mutation in a gene for a hydrolytic enzyme that renders the enzyme nonfunctional. What is the most likel

Question

Elan Coil [88]

2 years ago

14

A phagocytic cell has a mutation in a gene for a hydrolytic enzyme that renders the enzyme nonfunctional. What is the most likel

y effect of the mutation when this phagocytic cell ingests a pathogen

Biology

1 answer:

pshichka [43] · Answer 1 · 2022-09-19T21:05:24+03:00

Answer: The phagocyte’s ability to destroy the ingested pathogen is compromised and it will become inactive.

Explanation:

There are different hydrolytic enzymes. Lysozyme attacks cell walls of gram positive bacteria. Elastase is a protease. Collagenase attacks collagen, produced by some bacteria. Plasminogen activator is also a protease.

Loss of function of any one of these enzymes will reduce or prevent the breakdown of bacteria in the phagosome (vacuole) so that the phagocyte is inactivated.