Answer:
C) Through genomic imprinting, methylation regulates expression of the paternal copy of the gene in the brain.
Explanation:
The pattern of gene expression wherein either paternal or maternal gene is expressed in specific cells while the other one is prevented from expression is known as genomic imprinting.
In the given example, the maternal copy of the gene on chromosome 15 is expressed in brain cells while its paternal copy is not expressed in these cells. Hence, the pattern of expression of this gene is regulated through genome imprinting. One of the mechanism is methylation of cytidine residues of CpG islands of the DNA that are more frequently present within promoters of the genes.
When the cytidine residues of these sequences are methylated into 5-methylcytidine, the transcription factors do not bind to these promoters preventing the expression of these genes.
Hence, methylation of cytidine residue in CpG islands of the promoters of the gene present on chromosome 15 could have silenced its expression in brain cells.
Rickets is the disease in children in which an inefficient mineralization of the bone forming tissue causes deformities. This condition results in weak or soft bones in children, normally due to an extreme and prolonged deficiency of vitamin D. Vitamin D promotes the absorption of calcium and phosphorus from the gastrointestinal tract. The symptoms include bowed legs, stunted growth, bone pain, large forehead, and trouble sleeping among others.
Answer:
false
Explanation:
because it is not the correct answer for this question
Answer:
Telophase or in other words the final phase of mitosis
Explanation:
