There are four monoclonal antibodies (MAB) which specifically recognize double-stranded RNA (dsRNA) together with their use in new methods for detecting and characterizing dsRNA in unfractionated nucleic acid extracts. The specificity of the antibodies was analyzed using a panel of 27 different synthetic and naturally occurring nucleic acids. All four antibodies reacted in a highly specific manner with long dsRNA helices, irrespective of their sequence; no binding to single-stranded RNA homopolymers or to DNA or RNA-DNA hybrids were observed.
Monoclonal antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes.
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Answer:
it moves when carbon moves from fossil fuels to the atmosphere when fuels are burned when humans burn fossil fuels to power things and then most of the carbon quickly enter the atmosphere as carbon dioxide gas.
Explanation:
Answer:
The characteristics of allosteric enzymes are listed below.
Explanation:
1 They may have binding sites for regulatory molecules that are separate from the active site.
2 They tend to have sigmoidal curve of V0 vs [S].
3 They undergo conformational change as a result of modulator binding
