<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
The correct answer is the second choice - peer review process in scientific research exists in order to verify that the conclusions that are made are supported by the data. You cannot make a valid conclusion if you do not have enough evidence or data to prove it - this is why your peers have to go through your research to make sure everything is done according to the rules of scientific research.
Hope this helps.
Answer:
A. 90%
Explanation:
Only 10% can transfer from level to level.
