Proteostasis is mediated by chaperone proteins and protease systems, together with cellular clearance mechanisms such as autophagy and lysosomal degradation.
Chaperone proteins control assembly and inaccurate folding by binding to and stabilizing partly or completely unfolded protein polypeptides till the polypeptide chain is completely synthesized. Chaperone proteins also confirm the stability of unfolded polypeptide chains as they are being translocated into the subcellular organelles.
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Answer:
The researchers' experimental hypothesis was that changes in actin and myosin overlap would alter the number of myosin cross- bridges that could form within a sarcomere, and specifically that (Primer Section Key Terms O)
A. Increases in overlap favor more cross-bridges to form, increasing muscle force. muscle force. effect on muscle force. fiber) lengths.
Explanation:
Physiologists Alfred Gordon and Fred Julian and Andew Huxley investigated on the strianed muscle´s contraction properties, to demonstrate the way the muscle lenght is affected by changes in overlap between myocin and actin causing the number of cross-bridges increase , increasing muscle´s force as well.
No cross-bridge disruption is caused, nor litlle differences or minimal overlap so B, C and D options are not correct.
Answer:
Regarding the effect of pH on the reaction rate of three different enzymes, what the graph shows is that each enzyme works better at different pH (option A).
Explanation:
Enzymes are specialized protein molecules whose function is to contribute to faster reactions with lower activation energy. To fulfill this function, <u>enzymes must be in an optimal range of temperature and pH</u>.
The graph shows three enzymes, one in an acidic medium, one in a neutral medium and one in a basic medium. The reaction rate of each enzyme is similar, indicating that each is working at an optimum pH. The best interpretation that can be drawn from the graph is that each enzyme works best at a different pH.
The other options are not correct because:
<em> B. The variable "</em><u><em>temperature</em></u><em>" is not included in the graph.
</em>
<em> C and D. Since the comparison of the reaction rate of a single enzyme at different pH is not being made, the graph is not useful to indicate whether an </em><u><em>enzyme works better in acidic or basic conditions</em></u><em>.</em>