Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
![K_m_a=K_m[1+\frac{I}{K_i}]](https://tex.z-dn.net/?f=K_m_a%3DK_m%5B1%2B%5Cfrac%7BI%7D%7BK_i%7D%5D)
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
![52\mu M=40\mu M[1+\frac{1.5\mu M}{K_i}]](https://tex.z-dn.net/?f=52%5Cmu%20M%3D40%5Cmu%20M%5B1%2B%5Cfrac%7B1.5%5Cmu%20M%7D%7BK_i%7D%5D)
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM
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Reduce osteoblast activity while boosting osteoclast activity
osteoblast:
- Untreated celiac disease has a number of potential side effects, including the failure for children to reach their ideal bone density and adult bone loss, both of which raise the risk of osteoporosis. Following a gluten-free diet is the only way to treat celiac disease.
- As a result, celiac disease is common in both children and adults with low bone density. When celiac disease is discovered in an adult, the risk of osteoporosis is very significant (because they have gone longer without absorbing enough calcium and other nutrients).
- Osteoporosis is a bone disease that appears when bone mass, bone mineral density, or both drop or when the quality or structure of the bone deteriorates. This may result in a loss of bone density and an elevated risk of fractures (broken bones).
Learn more about osteoporosis here brainly.com/question/14601010
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Answer:
D. Fibrocartilage
Explanation:
In order to understand the question, we need to review the structure of intervertebral discs.
Intervertebral discs consist of two parts:
It forms the central part of the intervertebral disc and consists of mucoid substance.
It is composed of encircling layers of fibrocartilage and fibrous tissue surrounding the nucleus pulposus
<u>SLIPPED DISC:</u>
It is characterized by the protrusion of nucleus pulposus through the annulus fibrosus accompanied by the compression of spinal nerves.
Patient may present with loss of sensory sensations or pain or both.
<u>CORRECT ANSWER:</u>
From the above review, the correct answer is <u>D. fibrocartilage</u> as it forms the annulus fibrosus.
Answer:
60 beats per minute
Explanation:
heart rate is measured in minute, if he counted for 10 seconds, he would need to multiply that number by 6 to get his resting heart rate. 10×6=60
