Answer:
Statement 1,2,3,4 are correct.
#1. The reward/control circuits of the addiction pathway are hijacked by changes in brain chemistry altered by substance abuse.#1. The reward/control circuits of the addiction pathway are hijacked by changes in brain chemistry altered by substance abuse.
#2. The "go" circuit becomes overactive and drives compulsive substance use.
#3. The "stop" circuit does not function properly and is overridden by the "go" switch.
#4. Drug cravings hijack survival mechanisms in the old brain and override rational actions of the new brain.
Explanation:
Substance abuse
This is simply known as a maladaptive pattern of substance use. It occur over the last 12 months and can leads to impairment of occupational, physical, or social functioning in a man.
Substance dependence
This is when an individual is having substance abuse in addition with withdrawal symptoms, tolerance or a pattern of compulsive use. The down regulation in substance abuse can also leads to a defective reward circuit (flat feelings, depression etc ) and leaves user with a need for more or different drugs.