Answer:
1. Thyroid gland is the endocrine gland that is involved here.
2. TSH stimulation test did not show an increase in the output of thyroid hormones secreted from thyroid glands which makes it a primary disorder. The determination of TSH or TRH gives an idea about hypothyroidism if it is due to feedback inhibition of the pituitary or absence of TSH hormone from the pituitary, however, Circulating levels of TRH not necessary.
3. The feedback loop involves the following:
TRH hormone secreted from the hypothalamus triggers the anterior pituitary to secret TSH that in turn triggers the relapsing of the T3 and T4 levels by the thyroid glands. If there is a low level of T3 and T4 hormones then negative feedback takes place and increases the TSH output.
4. symptoms:
Not able to uptake the iodide into the cells of the thyroid gland
Defects in the conversion of iodide to iodine
tyrosine molecule iodization
secretion of the hormones from the Tg molecules
Less TSH receptors on the gland.
5. The chronic TSH stimulation due to negative feedback may cause hypertrophy of the gland, results in goiter formation.
6. synthetic hormone therapy is known as Synthroid such asT4 (L-thyroxine).
Explanation:
Fixed sample size:
In this fixed sample size the data is studied and checked in order to find a relationship. The benefits it is easy to produce, and with it less reliable outcomes can be given.
Sequential procedures:
→Sequential procedures helps while we are collecting the data.
→At an interim analysis, data collection can be stopped whenever the results are convincing enough to conclude an effect is present.
→Or otherwise the more data can be collected, or if needed the study can be terminated whenever it is extremely unlikely the predicted effect will be observed if data collection would be continued.
→In this two or more blocks of different sizes are prepared for testing.
→Pros being it provides better results and is less time taking, as we can stop once the relation is seen, con being it is difficult to perform.
Answer:
b. False
Explanation:
Channel proteins use passive transport, that is, they do not require energy such as ATP for transporting molecules.
