Answer: The answer is Anthocerophyta
Explanation: Anthocerophyta are widespread and occur in the temperate & tropical zones. The species of plants in this phylum have horn-shaped sporophytes which are known as "flower horn". As in other bryophytes, the sporophyte of this phylum remains attached to its parent gametophyte throughout its life, but unlike these other plants, the sporophyte continues to grow throughout its life; this happens as a group of cells at the base of the horn divide repeatedly. They also possess stomates, which exchange gases between the plant and the air.
The mitochondrial genome evolution in Anthocerophyta is closer to that of seed plants but not as dynamic.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Answer:
Depending on the stimulus, graded potentials can be depolarizing or hyperpolarizing. Action potentials always lead to depolarization of membrane and reversal of the membrane potential. Amplitude is proportional to the strength of the stimulus. ... Duration of graded potentials may be a few milliseconds to seconds.
Explanation:
