Explanation: Mutation can be defined as a permanent change in the nucleotide sequence of a DNA. There are basically three types of mutation: insertion, substitution or deletion. Insertion is a type of mutation in which one or more base pairs is added to a nucleotide sequence of a DNA. Substitution involves the replacement of one base pair with another in a nucleotide sequence of a DNA while deletion involves the total removal of one or more base pairs in a nucleotide sequence. A mutation can be silent if it affects non coding segments of a DNA or if it has negligible effect on the gene function, but most times mutations are deleterious.
