Answer: DF508 mutation. A Genetic, Hereditary, Autosomal and Recessive Mutation.
Explanation:
Cystic fibrosis (CF) is a recessive autosomal lethal disease, it is most common on Caucasoid populations. Its diagnosis is suggested by the clinical features of chronic obstructive pulmonary disease, persistent pulmonary colonization (particularly with mucoid Pseudomonas strains), meconium ileus, pancreatic insufficiency with or familiarity history of the disease. The FC gene is large, with about 250 Kb of genomic DNA, 27 exons representing about 5% of genomic DNA; encodes a 6.5 kb transcribed mRNA. This mRNA is transcribed into a protein of 1480 amino acid called CFTR (Regulator Transmembrane Conductance Cystic Fibrosis). When a three-base pair deletion, adenosine-thymine-thymine (ATT) identified in the CFTR gene, exon 10, it results in the loss of a single amino acid phenylalanine at position 508 of the protein. This mutation is called DF508; “D” stands for deletion and “F” for phenylalanine amino acid.
Answer:
Proteins are processed and modified in a successive manner to add or remove sugar as they move from cisterna to cisterna.
Explanation:
Golgi apparatus has a flat membrane disk in varies in number in stack, the number can be in between 3 to 20, however six is found in most of them. Cisternae can be separated in four classes cis, medial, trans, and TGN.
Proteins that come from the endoplasmic reticulum in cis type of cisternae after passed through cis to cis and move the protein in order to add or remove sugars to protein.
Thus, the correct answer is - Proteins are processed and modified in a successive manner to add or remove sugar as they move from cisterna to cisterna.
Answer: between the second and
third finger
The correct method of removing
a glass stopper is to grasp it between the second and third finger with the
help of the thumb. If the glass stopper is stuck, you can use the tap method by
using many gentle tap and keep on turning the flask. Another technique is to put
oil or use a flame to expose it to heat.
