Answer and Explanation:
The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.
Water molecules bond to each other in a covalent bond where they stay connected. They also have poles like a magnet, making it a polar molecule.
If water is no longer polar the surface tension would lower to the point where ice can no longer float, the water would freeze, cooling the climate considerably.
D. It provides information about the subject of an experiment.
Background research is research prior to conducting an experiment.
Explanation:
Background research is important so as to fully understand the variables that are being controlled and tested in an experiment, and their relationships that will give insights into how to design the experiment. The background research is also important in identifying the research problem setting up of a good hypothesis.Background research also reduces the rate of failure of an experiment due to proper preparation.
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