Responding to the environment is the characteristic of life that best describes the process of homeostasis. Homeostasis is the ability of a body or living organism to adjust its internalenvironment in order to maintain astable equilibrium regardless of the external changing conditions.
Answer:
the distance is increasing
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Answer:
by the sarcoplasmic reticulum's calcium ion pumps
Explanation:
Rigor mortis or postmortem rigidity, is a state caused by chemical changes in the muscles that occur post mortem and cause the limbs of the corpse to stiffen.
This occurs because after death, there is no cellular respiration and consequently, no oxygen nor ATP (ATP is required for the muscle relaxation).
Calcium enters the cytosol after death because it is released due to the deterioration of the sarcoplasmic reticulum and due to the breakdown of the sarcolemma. Ca2+ ions activate the formation of actin-myosin cross-bridging necessary for the contraction. Muscles are unable to relax, because myosin heads continue to bind with the active sites of actin and there is no ATP to destabilize the myosin-actin bond.
Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.