Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because...genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.
Explanation:
Archibald Garrod researched on alkaptonuria and proposed the ‘one gene-one enzyme’ hypothesis. This led to the finding that alkaptonuria is caused due to an inherited or “inborn error of metabolism”.
This hypothesis stated that each gene codes and responsible for a single specific enzyme which facilitates a particular step in the metabolic processes.
According to Garrod, a mutation of a particular gene leads to specific error or defect leading to a lack of a particular enzyme that takes part in the biochemical metabolic pathways. This disrupts the metabolic pathway at the specific enzymatic action point.
In alkaptonuria, it was found that the defective phenotype of dark urine is due to the inborn error happening during the waste elimination process.
In my personal experience In order to stay fit I do ballet and tennis. Those two things have helped me stay healthy and fit as well as creating hobbies! I also want to mention that I take vitamin supplements just in case if I am not for filling my normal vitamin intake from foods. So for example I take some vitamin C powder! I think it’s extremely important to work on your health and your physical activity because later in life all these things will affect you in a positive way so you won’t have to worry too much of your health considering the fact that you have been working on your health for the past years. I’ve also read that eating healthy can help you age backwards so you’ll look much younger at the age of 50 then you would if you didn’t take care of yourself physically. <3 have a great day
If your getting an iv of pure water and it goes into your veins their is a possibility it would lead to death.
Basketball is very rough and I know because I have played for 7 years. We should have more protection on our legs and maybe our arms because we do fall a lot and have to defend which gets very physical. I mean some do where knew guards but I think it should be a requirement