It totally depends upon whether modification is being done in somatic cells or germ cells. Somatic cells modification is ethically accepted because it doesn't pass from one generation to another generation but germline modification is considered as unethical because the modification will pass on to the next generation leading to the persistence of modification in future generations. The problem with genetic modifications is that the impacts of modifications are unpredictable, rather than being fruitful they may lead to lethal mutations so if it occurs in just somatic cells, then even if it is lethal/harmful, it will be confined to only that individual but if a lethal mutation occurs in germ cells then it will pass on to the subsequent generations and it will persist in all future generations.
As you move up to the food chain, the energy will decrease. This explains that the more the consumers, the lesser the energy that the last consumer will get from the sunlight. This is because each energy will decrease as it passes by the consumers because each consumers takes a portion of the full energy from the sun.
The types of evidence for evolution include
i) Changes in allele frequency over subsequent generations.
ii) When the population in question is examined it does not follow Hardy-Weiberg equilibrium.
iii) Signs of gene flow between populations.
iv) Presence of Sewall-Wright effects or genetic drift in the population.
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This is an example of negative feedback.
After a big meal, glucose levels in the bloodstream increases. The body recognises this change and goes through homeostasis, or the regulation of bodily state or internal environment.
The pancreas secretes insulin, which then binds to insulin receptors. This will result in the uptake of excess glucose from the bloodstream into cells and converted into glycogen to be stored in cells as energy storage molecules.
Since there is the counter effect of body (i.e. when blood-glucose concentration increases, the body sends a signal to decrease the blood-glucose concentration, this is called a negative feedback (instead of a positive feedback, which occurs if for e.g. the body signals cells to increase blood-glucose concentration even after blood-glucose concentration increased after a heavy meal).
Hope this helps! :)