<u>Answer:</u>
The correct answer option is E. translocation.
<u>Explanation:</u>
Philadelphia chromosome are CML and Philadelphia chromosome-positive ALL are the leukemias that are caused by a mutation.
This type of mutation which occurs in the occurs in the Philadelphia chromosome is called translocation.
Philadelphia chromosome contains a fusion gene which consists of the ABL gene and the BCR gene, producing the BCR-ABL oncogene which has an enzyme with an abnormal tyrosine kinase activity.
Endocrine gland - a group of cells that secretes substances into the blood or directly into an organ.
Differ from exocrine glands, endocrine glands have no ducts and secrete products (hormones) directly into blood.
Hormone - a substance produced by cells that helps specific groups of cells to perform specific functions. It is a product of endocrine gland which functions as chemical messengers to stimulate other cells.
Duct – a channel or tube that conveys a substance. It is part of the exocrine glands (such as salivary glands) which makes contact with surface .
Example - the relatively rigid covering of a plant cell, containing cellulose, hemicellulose, lignin, etc.<span>
non example - </span><span>Mycoplasma because it has no cell wall</span>