Answer:
The correct answer is lysosomes
Explanation:
Tay-Sachs disease is a genetic metabolic disorder in which a lipid called GM2 ganglioside builds in the brain which results in spasticity and death in childhood.
This disease is also known as lysosomal storage disease. Lysosomes are the major organelle that contains enzymes to breakdown molecules. In Tay-Sachs disease deficiency of hexosaminidase A occurs in lysosomes and this enzyme is needed to breakdown fats.
So due to this deficiency, it results in the accumulation of fats in the brain and spinal cord causing Tay-Sachs disease.
An example of <span>nonsubstituted alkane that can exist as one of only two isomers is Butane with molecular formula </span>

<span>.</span>
Isomers are those having the same molecular formula but different chemical structure.
Non-substituted alkane means it is not substituted by any other atom.It has only carbon and hydrogen atoms attached to it.
The answer to the statement above is TRUE. Recently, Permafrost has been seen in the regions of Eurasia and North America even though glaciers are not even common in this area. Normally, permafrosts are found in the polar regions. These are made up of frozen thick subsurface layer of soil that has remained untouched for years.