One of the most important legacies that World War I left behind was the idea of "total war," since up until WWI civilians and private homes were considered "off limits" in terms of targets.
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The correct answer is Isolationism
Becasue isolationism is where a country does not let anyone in or out of its borders and it does not participate in worldly afairs. It also has isolation in the name and the definition of isolation is the process or fact of isolating or being isolated.
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"c. The city became a central hub for trade, which contributed to the empires growth" best describes the effect of Constantine moving the capital to Constantinople, since it was a thriving metropolis.