<h2>CRISPR/Cas9</h2>
Explanation:
CRISPR can be used to reintroduce dystrophin back into the KO mouse
- CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats and is used to for gene editing
- CRISPR/Cas-mediated genome editing has been shown to permanently correct DMD mutations and restore dystrophin function in mouse models
- Germline editing by injecting zygotes with CRISPR/Cas9 editing component was first done in mdx mice by correcting the mutated exon 23
- Postnatal editing of mdx mice was then achieved using recombinant adeno-associated virus to deliver CRISPR/Cas9 genome editing components and correct the dystrophin gene by skipping or deleting the mutated exon 23 in vivo
- Germline and postnatal CRISPR/Cas9 editing approaches both successfully restored dystrophin function in the mice and same technique can be used for KO mouse model
4 cells will result. Each cell will have 20 Chromatids which is half a chromosome. once sexual reproduction takes place, these 20 chromatids will match with those from the other parent cell to form chromosomes
The answer is apex and base. To simplify, the apex of the heart rests on the diaphragm and from its base, the great vessels emerge. In addition, blood vessels that are nearer to the pumping heart and must enlarge to endure pressure variations are named elastic arteries and foramen ovale permits blood to pass from the right to the left atrium, therefore avoiding to pass the fetal lungs.
Plant cells have a cell wall, but animals cells do not. Cell walls provide support and give shape to plants. Plant cells have chloroplasts, but animal cells do not. ... Plant cells usually have one or more large vacuole(s), while animal cells have smaller vacuoles, if any are present.
