The four inferences were love, hate, war and the liberties of death.
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Phenotypes are the physical makeup of a living thing and genotypes are the genetic makeup of the living thing
Answer:
Water in the geosphere can be discharged into surface water, becoming part of the hydrosphere once again, or it could be drawn up into the roots of a plant and become part of the biosphere. Water in the biosphere can be released into the atmosphere through transpiration in plants, or respiration in animals.
It is true that it is possible for a population to not evolve for a while.
There is something called the Hardy-Weinberg theorem, which characterizes the distributions of genotype frequencies in populations that are not evolving.
There are 5 Hardy-Weinberg assumptions:
- no mutation
- random mating
- no gene flow
- infinite population size
- and no selection (natural nor forced).
You can see that some of these are kinda extreme and really hard to get, but with approximations, we can work.
For example, instead of an "infinite population size" we have enough with a really large population, such that genetic drift is negligible.
Concluding, yes, it is possible (but really difficult) for a population to not evolve for a while (at least, in nature), as long as the 5 assumptions above are met.
If you want to learn more, you can read:
brainly.com/question/19431143
