Answer:
Rickets disease.
Explanation:
Rickets disease occurs when there is a mineralization deficit of the extracellular bone matrix; as a result, the bones are soft, and they deform easily. The X-rays show thick epiphyseal plates because it is hyaline cartilage that should be calcified to become a bone. As there is a deficit of vitamin D, the mineralization of the plate can not be done, making bone is flexible and deformable.
The main cause for Rickets disease is a diet with low intakes of calcium and vitamin D, and poor exposition to the sun, which is the best way to produce vitamin D. These two components are crucial for the mineralization of the bones.
In the intervention group, 212 women (5.7 per 10,000 person-years) and 176 (4.7 per 10,000 person-years) received an ovarian cancer diagnosis (rate ratio [RR], 1.21; 95% confidence interval [CI], 0.99-1.48).
In the intervention group, there were 118 ovarian cancer-related deaths (3.1 per 10,000 person-years), compared to 100 in the standard care group (mortality RR, 1.18; 95% CI, 0.82-1.71).
1080 of the 3285 women who had false-positive test results underwent surgical follow-up, and 163 of them (15%) had at least one significant consequence.
Except for ovarian, colorectal, and lung cancer, there were 2924 deaths from other causes (76.6 per 10 000 person-years) in the intervention group and 2914 deaths (76.2 per 10 000 person-years)
Simultaneous screening with CA-125 and transvaginal ultrasound in comparison to standard treatment did not lower ovarian cancer mortality among women in the general US population. Complications were linked to diagnostic examination after a false-positive screening test result.
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