<span>Plants take in oxygen all the time for respiration.
Photosynthesis which begins by combining water and CO2, continues in the
"dark phase" in making the glucose molecule. Light is not used for this
part of the reaction so it is called dark , because light is needed for
the first part.
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Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
Protection of certain species is a very controversial topic. Many species like the mountain lion or jaguar that are near extinction in certain areas, are threats to human life. Another reason is that they could off set the food chain when they come back and be stonger than ever. For example the mountian lion could eat out the thriving white tail deer population which was struggling because of the mountain lion. And many people rely on white tail deer for food.
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Steam has the most energy because a particle has the most energy when it contains high internal energy. (Has the larger temperature)
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