Its D and you don't need to scream help ok?
Answer:
The enzyme’s active site binds to the substrate. Since enzymes are proteins, this site is composed of a unique combination of amino acid residues (side chains or R groups). Each amino acid residue can be large or small; weakly acidic or basic; hydrophilic or hydrophobic; and positively-charged.
Explanation:
A.Showing Aggression because if u show arrgrisiveness then you will/would end up starting a fight which is a negative way of dealing with it. Hope it helps mate