Answer:
I'm pretty sure the cancel eachother out
Answer and Explanation:
The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.
Question in English:
A female carries a recessive lethal gene (l) on one of her X chromosomes, and a normal dominant allele (L) on the other. What is the sex ratio to be expected in this woman's dependency if she marries a normal man?
Answer:
2/3 females
1/3 males
Explanation:
Females have two X chromosomes (XX) and males have an X and a Y chromosome (XY).
The genotype of the female is XLXl. The genotype of the male is XLY, since he is normal.
The possible genotypes are:
<u> XL Xl</u>
<u>XL</u> <em>XLXL XLXl</em>
<u>Y</u> <em>XLY </em><em>XlY</em>
<em />
All female offspring will be normal as they will always have one normal copy of the X chromosome from their father.
50% of the male offspring will be normal, but 50% will inherit the lethal gene from their mother.
Because the allele is lethal, that means XlY males will not be born.
That means 2/3 of the children will be females, and 1/3 will be males.
