A single base substitution mutation will be the least likely to cause a deleterious effect when the base change produces the same amino acid as the original.
<h3>What is a silent mutation?</h3>
This scenario is what we call a silent mutation.
What this means is that the mutation is almost undetectable due to its not affecting the protein that it will help to form.
This is possible thanks to how the genetic code operates, <u>different codons are able to code for the same amino acid.</u>
Therefore, there are mutations that do not affect the amino acid or the protein.
Therefore, we can confirm that a mutation will have no negative effects if it is a silent mutation, meaning that the substitution of a base pair happens to code for the same amino acid as the original.
