Question

A single base substitution mutation is likely to have a less deleterious effect when the base change exhibits which of the following results

Answer 1

A single base substitution mutation will be the least likely to cause a deleterious effect when the base change produces the same amino acid as the original.

What is a silent mutation?

• This scenario is what we call a silent mutation.
• What this means is that the mutation is almost undetectable due to its not affecting the protein that it will help to form.
• This is possible thanks to how the genetic code operates, different codons are able to code for the same amino acid.
• Therefore, there are mutations that do not affect the amino acid or the protein.

Therefore, we can confirm that a mutation will have no negative effects if it is a silent mutation, meaning that the substitution of a base pair happens to code for the same amino acid as the original.

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