The answer is the third one, both
The dicrotic notch represents the nadir point that occurs immediately after the closure of the aortic valves and precedes the secondary dicrotic wave. The T wave represents ventricular repolarization. This is followed by ventricular relaxation, during which the ventricles falls. The dicrotic notch is a short-lived decrease in pressure in the ascending aorta, which occurs following closure of the aortic valve.
The part of the brain that is associated with pleasure and reward. Anterior cingulate cortex and striatum (triathlete.com)
If you mean prescription drug overdose, then ever 19 minutes <3
With high enough doses of alcohol, respirations stop first; which ultimately leads to death.
