Answer:
Upon binding of integrins with such synthetic peptides, disrupts the receptors, and make them unavailable to bind with fibronectin or laminin.
It would impact in inhibition of binding of cells to extracellular matrix (ECM). It is an important strategy that disrupts the adhesion of integrins and ligands. It can have significant role in tumor invasion and metastasis.
I suppose that
this information will help you.
Osteoporosis
- a chronic, progressive system, metabolic diseases of the skeleton, or a
clinical syndrome manifested in other diseases, which is characterized by
decrease in bone density, a violation of their microarchitectonics and
increased fragility, due to metabolic disorders of bone tissue with a
predominance of catabolism of the processes of bone formation, decreased bone
strength and increased risk of fractures.This definition refers to osteoporosis
diseases of the musculoskeletal system and connective tissue (ICD-10) and
completes his term "metabolic or metabolic diseases."
Tt x Tt gives 3 Tall(Tt, Tt, TT) and 1 Short(tt) so the probability would be 75 percent
