Tay-Sachs disease is caused by mutations in the HEXA gene and inheritance is autosomal recessive . The HEXA gene gives the body instructions to make part of the beta-hexosaminidase A enzyme, which is needed to break down a substance called GM2 ganglioside.
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<span>Regions of DNA that read the same regardless of the direction are called Palindromes. The sequence of nucleotides is the same whether you start from the 3' end or the 5' end. Palindromes may occur due to chromosomal inversion or due to breakage.</span>
As the vast Pangea continent broke apart due to tectonic
movements, the movement of animals was restricted to their continent hence gene flow
between populations was reduced. As the tectonic plates moved across latitudes, their climate
changed and consequently, the fauna on
the continents. This necessitated for speciation of the offspring population from parent
population so as to adapt to the
new habitats. Some animals were unable to adapt
while others such as the reptiles, adapted well.
The valves prevent the backward flow of blood.