Answer:
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Answer:
See explanation
Explanation:
The drug thalidomide with molecular formula C13H10N2O4 was widely prescribed by doctors for morning sickness in pregnant women in the 1960s.
The drug was sold as a racemic mixture (+)(R)-thalidomide and (-)(S)-thalidomide.
Unfortunately, only the (+)(R)-thalidomide exhibited the required effect while (-)(S)-thalidomide is a teratogen.
This goes a long way to underscore the importance of separation of enantiomers in drug production.
Therefore, all the teratogenic effects observed when using the drug thalidomide was actually as a result of the presence of (-)(S)-thalidomide, the unwanted enantiomer.
Answer:
a. withdraws electrons inductively
b. donates electrons by hyperconjugation
c. donates electrons by resonance
d. withdraws electrons inductively
Explanation:
a. The bromide ion is a highly electronegative ion (in the halide series). Electronegative substituents on acids increase the acidity by inductive electron withdrawal method. The higher the electronegativity of a substance, the greater the acidity. The halogens have this order of electronegativity:
F > Cl > Br>I
b. The carboxyl groups have a stabilization of the sigma and pi bonds. This is achieved through a special delocalization of electrons. Because of the delocalization, hyperconjugation is the result effect.
c. The NHCH₃ group has a highly electonegative nitrogen atom that pulls the electron cloud towards itself. In this case, it withdraws electrons inductively. As a result, it donates electrons by resonance.
d. The OCH₃ group has a highly electonegative oxygen atom. This oxygen atom withdraws electron cloud towards itself. As a result, it withdraws electrons inductively.
If you mean how many electrons an atom contains then this is the same as the atomic number of the atom. For example, the atomic number of oxygen is 8 so it contains 8 protons. Since in a stable atom, the number of protons is equal to the number of electrons, oxygen contains 8 electrons.
If you have an ion and you want to know how many electrons it has lost or gained, you look at the charge. If it is a 2+ ion then it has lost two electrons, if it's a - ion then it has gained an electron. The number of electrons in an ion is the atomic number +/- the charge shown. For example a Mg2+ ion would have 10 electrons as a magnesium atom has 12 electrons and loses two to form the 2+ ion.