Answer:
1. Histone methylation occurs at different amino acids: c. Activates and inactivates
2. A transcriptional binds an enhancer sequence: d. No effect
3. Histone acetyltransferase attach acetyl groups to the N-terminus of histones: a. Activates
4. Histone deacetylases remove acetyl groups from the N-terminus of histones: b. Inactivates
Explanation:
Epigenetics refers to the mechanisms associated with changes in gene expression which do no involve alteration in DNA sequence. Epigenetic marks include DNA methylation and histone modifications (acetylation, methylation, phosphorylation, etc). These mechanisms act together in order to regulate gene expression at specific genomic sites (<em>loci</em>). Histone methylation is an epigenetic mark involved both in transcriptional repression and transcriptional activation. For example, trimethylation of the histone H3 at lysine 4 (H3K4me3) has been associated with transcriptional activation, while dimethylation of histone H3 at lysine 9 (H3K9me2) is often involved in transcriptional repression. Moreover, histone acetylation by histone acetyltransferases (HATs) is an epigenetic mark that is involved in transcriptional activation and chromatin decondensation, while histone deacetylation by deacetylases (HDACs ) is generally associated with gene repression. However, it is important to highlight that there are exceptions to this rule (for example, acetylation of the histone H4 lysine 20 is associated with gene repression). Finally, transcriptional activators are proteins that bind to enhancers in order to recruit coactivator proteins/complexes and thus activate transcription.
Increasing the number of capillaries associated with alveoli would be expected to increase carbon dioxide being carried to alveoli.
Alveoli are the very small air sacs at the end of the bronchioles. Each alveolus is cup-shaped with thin walls, and It is surrounded by networks of blood vessels which are called as capillaries that also have very thin walls. The oxygen we breathe gets into the blood through the alveoli and capillaries. The Red blood cells travel through the capillaries. Alveoli's walls share a membrane with the capillaries. Oxygen and carbon dioxide get in and move freely between the human respiratory system and the bloodstream.
Oxygen molecules are attached to red blood cells, which travel back to the heart, and at the same time, carbon dioxide molecules in the alveoli get out of the body.
Learn more about alveoli here
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As this question as biology at the top,socialization is a social process with strong biological components that interact with social and cultural frameworks and factors
I am not really sure are there multiple choice questions if so I need to see them.
Answer:
A fusion protein can be sythesized to carry a specific tag, which is useful in identifying the proteins in various experiments. Fusion proteins with the FLAG epitope bind to specific anti-FLAG antibodies and carry this extra sequence: Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys. The bioteh company that sells anti-FLAG antibodies states that fusion proteins carrying the Flag epitope display the sequence on the surface of the protein. This is likely <u>A short hydrophilic 8-amino acid peptide</u> because<u> of its hydrophilic nature</u> of the eight residues are <u>Likely to be located on the surface of the fusion protein</u>, making FLAG highly <u>Specific and easily accessible for cleavage by enterokinase </u> and likely to interact<u> with other epitope and domains</u> Al with water.
Explanation:
FLAG, a short hydrophilic peptide consisting of 8 amino acids have been widely used as a fusion tag for purification and detection of a wide variety of recombinant proteins. the 3× FLAG system is an improvement upon the original system by fusing 3 tandem FLAG epitopes (22amino acids). detection of fusion protein containing 3× FLAG is enhanced up to 200 times more than any other systems.