<span>By definition, the two determinants of mean arterial pressure are cardiac output and total peripheral resistance. It has been shown that Lasix decreases cardiac output and total peripheral resistance. Diuretics increase urine production, so it will lower mean arterial pressure.</span>
I don't know what you mean by your question, but if you are making an appropriate title it will be good if you title it that is unique and would want to make your reader more interested with your story. Just trying to help :)