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denpristay [2]
2 years ago
12

Q/Clinical applications of the IL1 (IL1= Interleukin-1 )beta and

Medicine
1 answer:
Lady_Fox [76]2 years ago
3 0

Answer:

Much debate has focused on the relative importance of interleukin 1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) in the pathophysiology of rheumatoid arthritis (RA). The production of these cytokines by synovial macrophages is tightly regulated by cell-cell contact with T cells. During this contact, several surface molecules are implicated in contact mediated cytokine production, including CD40 ligand, CD11b/c, and CD69. Apolipoprotein A-I, an acute phase reactant (APR) that declines during systemic inflammation (reverse APR), inhibits cytokine production by interfering in the T cell-monocyte interaction. Although the effects of IL-1 and TNF-alpha overlap, they have somewhat differing roles in RA on the basis of evidence from several animal models. TNF-alpha appears to play a more important role in triggering events leading to inflammation both locally and systemically, whereas IL-1 is more involved at the local level in processes leading to cartilage and bone destruction and in impeding cartilage repair. However, IL-1 and TNF-alpha strongly synergize in numerous biological functions, both in vitro and in vivo. Blockade of IL-1 and TNF-alpha simultaneously provides favorable effects in collagen and adjuvant induced arthritis, illustrating the importance of both cytokines.

Explanation:

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Which category of drugs produces moderate physical dependence but high psychological dependence? A. schedule 1 B. schedule 2 C.
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What could happen if the Repackaged medication is stored improperly
Kisachek [45]

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It could loose its propeties and not work or in some cases hurt you or even poisen you

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3 years ago
Do pharmacist licenses have to be on display? the original or official copy? is a photocopy ok? can you obscure your address on
Pie

<u>Yes</u>, Pharmacist licenses should be on display. License copies can be <u>acceptable</u> and there is <u>no</u> rule against obscuring address on the copy displayed to the public.

Every license to practice pharmacy shall be conspicuously displayed by the person to whom the same has been issued in the pharmacy, drug store, or place of business, if any, of which the said person is the owner or part owner or manager.

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To learn more about RDL licenses, here

brainly.com/question/1358383

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4 0
2 years ago
In what part of the spinal cord would you expect to find myelinated axons?
kolezko [41]

Answer:

The answer to the question: In what part of the spinal cord would you expect to find myelinated axons, would be, in the white matter of the spinal cord.

Explanation:

The spinal cord, the roadway and connection between the brain and the rest of the body, and a vital part of life itself, is formed by covering tissue, fluid, and most importantly, by the neuronal bodies and axons that form the entire system of the CNS, and ANS, and which also connect these systems with the PNS (peripheral nervous system), and the different organs. One visual characteristic of the cord is it having two colors, white and gray. The white matter surrounds the gray matter. The reason for this white color in the white matter, which is really the connecting filaments that go up and down the CNS, and connect with the gray matter, is that white matter neurons and axons are covered by myelin, an insulating and cushioning covering that surrounds the cell´s axons and also helps the nerve impulses move much faster and with higher precision, than in the white matter.

3 0
3 years ago
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