Plants have large Vacuoles because they keep their water stored inside. Since plants live almost entirely off of water, their vacuoles are larger unlike those in an animal cell.
The disease is mainly caused by a lack of a slippery substance in the lungs called surfactant. This substance helps the lungs fill with air and keeps the air sacs from deflating. Surfactant is present when the lungs are fully developed.
https://medlineplus.gov/ency/article/001563.htm
Answer:
DNA packaging is the method to convert long DNA into condensed chromosomes. Histone protein is responsible for basic level packaging of DNA into the nucleosome. Histone proteins are positive in nature that neutralize the DNA's negative charge.
A nucleosome consists of eight histone proteins which wraps around 147 bp of DNA. Each nucleosome has linker histone which forms chromatosome.
The next level of organization is the compaction of nucleosome into approx 30nm diameter fiber due to the attraction between nucleosomes.
Then protein condensin helps in making the 30 nm chromatin fiber to condense more to become a chromosome which is 1000 fold smaller than its original length.