The three methods of carbon dioxide transport in the blood are dissolution in blood plasma, binding to hemoglobin, and carried in the form of bicarbonate. About 7% of the carbon dioxide is dissolved in the blood plasma. The majority of the remaining 93% is carried as part of the bicarbonate buffer system while the rest binds to hemoglobin.
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Answer:
Citrate Synthase facilitates the formation of citrate by deprotonating Acetyl CoA and by protonating the carbonyl oxygen of oxaloacetate
Explanation:
Citrate synthase is a key enzyme in the citric acid cycle that functions to catalyze the formation of citrate from oxaloacetate and acetyl-CoA: acetyl-CoA + oxaloacetate + H2O >> citrate + CoA-SH (Coenzyme A ). This enzyme contains three amino acids at its active site that work together to catalyze the conversion of acetyl-CoA and oxaloacetate into citrate. This active site acts by abstracting (deprotonating) a proton from the alpha carbon of Acetyl CoA which serves as the nucleophile. Subsequently, the active site of the enzyme also protonates the carbonyl oxygen of oxaloacetate, which then suffers nucleophilic attack and thereby facilitating nucleophilic substitution reaction.
C. The branch of biology that deals with interactions of organisms with each other and the surroundings :)
