Explanation:
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Then I will give you answer
Answer:
Explanation:
The Escherichia coli catabolite gene activator protein (CAP) is a DNA binding protein involved with the transcription of several genes, including those that code for enzymes involved in the metabolism of certain sugars (i.e. lactose, maltose, and arabinose.) <u>Basically, CAP is responsible for the global regulation of carbon utilization.</u> Upon binding cAMP, CAP binds to a conserved DNA sequence from which it can either activate or repress transcription initiation from various promoters. In some cases clusters of several promoters are all controlled by a single cAMP-CAP complex bound to the DNA.
Once CAP has bound cAMP, the protein exhibits a higher affinity for a specific conserved DNA sequence. When the intracellular level of cAMP increases, the second messenger is bound by CAP and the cAMP-CAP complex binds to the DNA. Once bound, it is able to stimulate the transcription of the aforementioned genes. DNA bound by the CAP-cAMP complex is bent by ~90 degrees. This DNA bend, coupled with a protein-protein interaction between CAP and RNA polymerase is thought to be the mechanism by which CAP regluates transcription initiation on the chromosome.
Natural levels of nitrate in Minnesota groundwater are usually quite low (less than 1 milligram per liter [mg/L] of nitrate-nitrogen). However, where sources of nitrate such as fertilizers, animal wastes, or human sewage are concentrated near the ground surface, nitrate may seep down and contaminate the groundwater. Elevated nitrate levels in groundwater are often caused by run-off from barnyards or feedlots, excessive use of fertilizers, or septic systems.
Wells most vulnerable to nitrate contamination include shallow wells, dug wells with casing which is not watertight, and wells with damaged, leaking casing or fittings.
Nitrate contamination of a well is often regarded as a first sign of deteriorating groundwater quality.
Answer:
When patient takes in antibiotics the resistance bacteria gets a competitive survival advantage over the normal sensitive bacteria and hence grows faster.
Explanation:
- Bacteria can acquire resistance by taking in plasmids containing MDR (Multi-Drug Resistance) gene cassettes. The MDR genes produces proteins that can:
- Render the antibiotic ineffective to act on its target by inducing chemical modifications on the drug.
- Promote efflux of the drug from the bacterial cell so that the drug cannot act upon its target.
- When a healthy person ( having no prior exposure to the antibiotic) is infected by bacteria ( both sensitive and resistant varieties):
- A competition develops for the host cells and nutrients between the sensitive and the resistant variety.
- This mutual competition restricts either of the sensitive or resistant bacterial strain to grow profusely.
- When a person (having prior antibiotic exposure), gets infected by bacteria ( both sensitive and resistant varieties) and is exposed to the same antibiotic:
- The sensitive variety, due to its sensitivity towards the drug, gets killed.
- The resistant variety, due to its MDR genes, bypasses the lethal effect of the drug and survives.
- These surviving resistant bacteria can now infect all the available host cells and utilise all the available nutrients without facing any competition and multiply rapidly.
A planet in our solar system is like the earth it is stable to live on but anything can happen while you are on it but and a dwarf planet it is not for everyday life so humans can not live on a dwarf planet like they could on one in the solar system
