Local anesthetics inhibit nerve conduction in a reversible manner without altering the nerve. The inhibition appears rapidly and for a longer or shorter duration depending on the products and the concentrations used. The extent of the territory rendered insensitive to pain depends on the modes of administration of the local anesthetic, either at the level of the nerve endings, or at the level of a nervous trunk, for example.
They act at the level of the neuronal membrane by interfering with the process of excitation and conduction. The anesthetic crosses the axon membrane, rich in lipids, in the form of base before taking up a cationic form on the internal face of the neuron where the pH is more acidic.
At this level, there is a blockage of nerve conduction by decreasing the membrane permeability to sodium ions that occurs during the depolarization phase. As the progression of the anesthetic action along the nerve increases, the threshold of excitability increases and the conduction time increases. This is completely blocked from a certain concentration of local anesthetic.
The nerve fibers are unequally sensitive to the action of local anesthetics: they disappear in order: the painful, thermal, tactile sensations.
Answer:
A, C, D and E
Explanation:
In the assessment of legs, there are many systems that are combined for that part of the body to function optimally.
The reason that all the options are relevant in this question (except for B) specifically referring to legs, is that option B (the cardiovascular system) is not a main indicator of a problem with that part of the body specifically.
If something is wrong with the leg of a patient, there is a small likelihood of it being related to the cardiovascular system, because if the cardiovascular system is causing something to be wrong in the legs, it should not be limited to that section of the body. Hence, the other options are correct, but not option B.
Discerning is the answer to your question.
Right bundle branch block. should also be visible in v2
Either give them a new home
Pass them off and say no backsies
Kill them and hide the body
Hope these help