Question

In the marine mollusk, Aplysia, serotonin binds to a G-protein-coupled receptor and activates a Gs subunit. The resulting activation of PKA leads to phosphorylation and closure of K channels. What effect would this have on the cell

Answer 1

The serotonin binds to a G-protein -coupled receptor and activates a G-subunit . This results in activation of PKA and closing of the potassium channels. This will subsequently decrease the influx of potassium ions into the cell, and lead to depolarization of the cell. This changes the membrane potential of the cell.

Aplysia are sea slugs which fall under the category of mollusks. Serotonin is a hormone which is responsible for the transfer of electrical signals from the brain to different parts. In this particular mollusk, serotonin was studied to find that it is an essential neurotransmitter that is responsible for the maintenance of synaptic plasticity in the neurons. Synaptic plasticity is the feature which is essential for the communication of neurons. This is the modification which occurs at the synapses during the transmission of synapses. Without this activity, the transmission of signals would be impossible.

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