Activation of G-protein coupled receptors contribute to the long-term enhancement of the gill withdrawal reflex in Aplysia but is not involved in the short-term enhancement of the reflex.
The gill and siphon withdrawal reflex (GSWR) of the sea hare <em>Aplysia californica</em>, also known as a giant shell-less sea snail or sea slug, is an involuntary defence response that the sea hare does automatically. When the animal is startled, this response causes the sea hare's sensitive siphon and gill to retract, protecting them from further damage. Because of the ease of use and fairly large size of the underlying neuronal circuitry, the species<em> Aplysia californica</em> is utilized in the field of neuroscience research for the purpose of investigating the cellular basis of behaviour, such as habituation, dishabituation, and sensitization.
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