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mariarad [96]
2 years ago
5

Why is the drug actinomycin used only in research applications or in the treatment of cancer?

Health
1 answer:
Oxana [17]2 years ago
8 0

Actinomycin is used only in research applications or cancer treatment because it is active against both prokaryotic and eukaryotic cells.

<h3>How does actinomycin work?</h3>
  • Actinomycin D inhibits RNA synthesis in both prokaryotic and eukaryotic cells thus blocking transcription.
  • Actinomycin was first isolated from <em>Streptomyces antibioticus</em>.
  • These bind to the DNA at the site of transcription initiation complex and prevent the activity of DNA dependent RNA polymerase.
  • By blocking the metabolic machinery of cells (RNA synthesis), actinomycin prevents the growth of cells. Therefore used in cancer treatment to prevent uncontrolled proliferation of cells.
  • As it can also act on eukaryotic cells so it is not used as an antimicrobial drug as it can harm the cells of our body.
  • However it can be used in research to prevent microbial growth in petri plates.

Learn more about antibiotics here:

brainly.com/question/7385027

#SPJ4

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