Question

on the basis of this information, are the r1 and sub mutations intragenic suppressors or intergenic suppressors?

Answer 1

r1 and sub-mutations are intragenic suppressors. Second mutations in the same gene, known as intragenic suppressors, allow the mutant gene product to resume its original function.

A suppressor is a secondary mutation that compensates for the main mutation's loss of function. An "intragenic suppressor" is a suppressor mutation that occurs inside the same gene, whereas a "intergenic suppressor" is a suppressor mutation that occurs in a distinct gene.

Intergenic suppressor mutation is a second mutation that mitigates the impact of a mutation in one gene by a mutation elsewhere in the genome, whereas intragenic suppressor mutation refers to a second mutation within the same gene that restores the function of the mutant gene product.

A secondary mutation called a suppressor is one that compensates for the main mutation's loss of function. The terms "intragenic suppressor" and "intergenic suppressor" are used to describe suppressor mutations that take place within the same gene and, respectively, in distinct genes.

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