A patient's doctor suspects pernicious anemia because of the patient's macrocytic anemia. A conclusive diagnosis of pernicious anemia would be made with a test for intrinsic factor antibodies.
<h3>What are intrinsic factor antibodies?</h3>
Immune system-produced proteins called intrinsic factor antibodies are linked to pernicious anemia. This test finds circulating intrinsic factor antibodies (IF antibodies) in blood. Known as parietal cells, these specialized cells line the stomach wall and generate a protein known as the intrinsic factor.
<h3>Define macrocytic anemia.</h3>
When your bone marrow creates excessively large red blood cells, it causes the blood condition known as macrocytic anemia. Red blood cells cannot operate normally without the nutrients that these aberrant blood cells lack. Although macrocytic anemia is not a dangerous sickness, it can have serious health consequences if untreated.
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