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Solnce55 [7]
1 year ago
8

what happens to the rf value of your compound if you change your solvent from methylene chloride to methanol?

Chemistry
1 answer:
Masja [62]1 year ago
6 0

Rf values may vary. Rf values vary depending on the material and solvent. The solvent that is used will alter the Rf value.

Rf values are typically higher for low polarity chemicals compared to higher polarity ones. Generally speaking, as polarity of a compound increases, so does its adsorptivity (i.e. the more polar the compound then the stronger it binds to the adsorbent). Solvents get more eluting as they become more polar.

The greater the compound's polarity, the more readily it will bind to the adsorbent, the closer it will come to the baseline, and the lower its Rf value. Many scientists use normal-phase flash chromatography with dichloromethane and methanol as the mobile phase to purify polar organic molecules. Due to methanol's high polarity and protic chemistry, it can frequently be difficult to optimize this solvent system.

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