Kupffer cells are the first innate immune cells and protect the liver from bacterial infections. They are phagocytic and are responsible for clearing hepatic sinus blood of bacteria and other foreign materials.
What are Kupffer cells made of?
These cells are derived from bone marrow stem cells or monocytes and are highly active in removing particulate matter and toxic or foreign substances that appear in the portal blood from the intestine.
What cell removes bacteria in the liver?
Kupffer cells rapidly capture bacteria from the blood and eliminate them, while still allowing for the induction of adaptive immunity.
Thus, kupffer cells are responsible for protecting the liver from bacterial infections.
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