Osteoporosis is the disease of the low bone mass and most often caused by the increase in the bone resorption that is not in sufficiently compensated for by the corresponding increase in the bone formation. As result gut-derived serotonin (GDS) inhibits the bone formation, we can asked whether hampering its is biosynthesis that could treat the osteoporosis through the anabolic mechanism (that is, by increasing bone formation).
We can synthesized and used the LP533401, a small of molecule inhibitor of the tryptophan hydroxylase-1 (Tph-1), the initial enzyme in the GDS biosynthesis. or the Oral administration of this small molecule once daily for up to the six weeks that acts as prophylactically or therapeutically, in the dose-dependent manner, to treat the osteoporosis in the ovariectomized the rodents because of an isolated increase in the bone formation. These results that provide a proof of the principle that have inhibiting the GDS biosynthesis that could become a new anabolic and treatment for osteoporosis.
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Answer:
A) Storage
Explanation: Hope it helps!!
Answer:
B)inducible
C. )extracellular enzyme
Explanation:
Catalase is an enzyme that is engaged during the the decomposition of hydrogen peroxide to form water and oxygen, it is posses by all living organisms because of their exposure to oxygen, hence it protect the cell from oxidative damage by reactive oxygen species.
Catalase enzymes function in our liver by breaking down harmful hydrogen peroxide into oxygen and water ,during this reaction , the bubbles of oxygen gas that escape create a foam that will help to disinfect any surface touch by the raw liver during this process. Catalase enzymes are extracellular enzyme and are inducible.
Explanation:
Melanin is the pigment which absorbs UV light and it is present in skin and gives black colour to it.As we can see africans usually have black skin as they have to face direct uv light.
Answer:
The isobars that are close to each other indicate strong winds
Explanation:
The isobars that are close to each other indicate strong winds. The gap or spacing between two adjacent isobars represent the pressure difference between them. lower the gap between then higher is the chances of pressure difference. Therefore when two isobars are very close to each other then strong wind prevail due to movement of air to fill vaccum space